NetGuido

The tremors characterize Parkinson’s disease, a neurodegenerative disease like Alzheimer’s disease or Huntington. Yet these movements are emerging as the face of evil that eats away at the brains of patients. Each gesture of daily life becomes difficult to catch a cup, dressing only… All voluntary movements are slowed down irretrievably.scanner maaldie Parkinson Scanner brains healthy and suffering from the disease Parkinson. DR Images Some neurons defective The brain is different in all regions which have a function well established:



memory, pain, pleasure, logic, and so on. Do you ever wondered how you come to lift the arms or write? All our movements are controlled by mechanisms nervous under the auspices of nerve cells: dopaminergic neurons. These cells have a neurotransmitter, a chemical molecule responsible for the communication of information between neurons, dopamine. What is it? This molecule is the precursor to another neurotransmitter family: catecholamines. The adrenaline, which is palpiter our heart, and norepinephrine, are representatives and especially the chemicals involved in movements, exciting or inhibiting the muscles of organs. In Parkinson’s disease, these neurons are rich in dopamine dysfunction where the tremor. Currently, drug treatments can reduce symptoms, the last resort is surgery for more severe cases. Electrode implants make up the défiscience neurons. The iron responsible
For years, researchers suspect as an ion fauteur disorder, iron. In the laboratory, they have resorted to chelated iron, ie, molecules capable of imprisoning ion target and eliminate it. In mice suffering from Parkinson’s disease, injecting these chelated iron significantly reduces symptoms. But in humans, we still need to know where to allocate the iron?
A team of researchers from the CNRS, the ERSF but also of the University of Seville coordinated by Richard Ortega has used a new technology: the nano probe developed X-ray synchrotron in Grenoble. This fine imaging can view all chemical compounds present in the cells. Here scientists have focused on the dopamine neurons and distribution of iron.
The results published in PlosOne in October 2007 show the creation of complex iron-dopamine. Evidence suggests that dopamine acts as a sensor of iron, thus increasing its concentration in nerve cells. These complexes are highly toxic and impede the smooth functioning of dopaminergic neurons; indeed small vesicles of these cells in patients are poor neurotransmitter. Therefore, information is circulating properly. This discovery opens up great prospects for treating tremors.